Transferring and assigning 1H-15N HSQC's


If you have chemical shifts for a protein (e.g. from BMRB, or even from your own protein and want to work under different conditions) the following script can easily insert the assignments into a .xpk file.

First you need to create a ppm.out file for the chemical shifts in the following format:

 16.N      120.102 1
 16.HN       8.059 1

etc......

Then copy the following file to your directory

ass.tcl

source it using the following command at the NMRVIEW console:

source ass.tcl


if you have placed this is a different directory you will need to include the full path


the following command will now allow you to assign a peak

tocass

If it is unique the .xpk is updated.

This can also be done using the "identify" command. However, you can make the command loop over all peaks by issuing the following command in the NMRVIEW console:


for {set i} {$i < 200} {incr i} {
g $i
tocass
puts $i
}


This will now assign all the unambiguous peaks automatically.

Any problems see me (Mike)